Ignorance is the root cause of all suffering. We tend to forget the physical suffering but not the emotional disturbances. We carry these sufferings with us. For what!! Did we bring these sufferings with us to the earth? No, we collected them from here with our ignorance.
But unfortunately, we humans hate change. We are ready to change, if we are offered more wealth, high position etc. But we are not ready to leave the fruits that we have reaped from here. This is against nature. The end result of desisting change is nothing but suffering.
To end suffering - know your desires and how your mind works. Stop being the slave of mind and desires.
The body has to perish. Accept it. Learn to severe attachment to the body. Be prepared to go away at anytime. And go away happily.